fT4/fT3 Ratio Calculator for Hashimoto's Therapy
About fT4/fT3 Ratio for Hashimoto's Therapy
The fT4/fT3 ratio is an important indicator for assessing thyroid function and optimizing treatment in Hashimoto's thyroiditis.
Interpretation:
- Optimal ratio: 3.0 - 3.5
- < 3.0: May indicate excessive T4 to T3 conversion
- > 3.5: May indicate poor T4 to T3 conversion
Clinical Significance:
The fT4/fT3 ratio helps clinicians assess the efficiency of T4 to T3 conversion and adjust thyroid hormone replacement therapy in Hashimoto's patients.
References:
- Wiersinga WM. Thyroid hormone replacement therapy. Horm Res. 2001;56 Suppl 1:74-81.
- Gullo D, Latina A, Frasca F, et al. Levothyroxine monotherapy cannot guarantee euthyroidism in all athyreotic patients. PLoS One. 2011;6(8):e22552.